Answer :
The correct answer is option B. i.e.invention of the microscope. Galileo Galilei invented the microscope and showed its use. Sir Issac Newton invented some part of the calculus, Also invented Newton's Laws of motion and the universal gravitation theory.
The correct answer is B. Although it is unknown who invented the microscope, Sir Isaac newton developed calculus along with Gottfried Leibniz. Sir Isaac Newton is also known for his three laws of motion. Newtons discoveries and theory set the stage for many other advancement in astronomy.
Hopes this helps!