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Several enzymes are needed for DNA replication. As enzymes are proteins hence, it can be said that many proteins are needed for the replication of DNA.

Some of them are:

Helicases are required for unwinding the DNA.

Topoisomerases are required for unwinding the supercoiling of the DNA.

Ligases are proteins or enzymes which join the nucleotides to make up a strand.

DNA polymerases are involved in synthesizing the new strand of DNA.

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