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A 10 year old male neutered West Highland White Terrier with a history of 1st degree AV block is admitted to the clinic for a routine dentistry. All of his pre-anesthetic lab work has come back normal. Which of the following anesthetic drugs would be most contraindicated in this case?
Dexmedetomidine

Answer :

Dexmedetomidine

Explanation:

  • Dexmedetomidine (Dexdomitor) is an alpha 2 agonist of which the major side effect is bradycardia. Patients with 1st degree AV block are often already bradycardic, and the AV block could be made worse by giving an alpha 2 agonist
  • While diazepam, butorphanol, and acepromazine all cause different degrees of sedation, they do not cause significant changes in heart rate or contractility. Acepromazine causes vasodilation, which can lead to hypotension, but it is anti-arrhythmic and can actually help stabilize the heart
  • Hence, the right answer of anesthetic drug is " dexmedetomidine"

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