Answer :
METALWORKING was a major industry in the middle colonies; TOBACCO, COTTON, and SUGAR were predominant in the southern colonies.
The Middle Colonies had an economy based on industrial production, which is why metalworking developed favorably in that area.
The Southern Colonies, on the other hand, had a distinctly rural and agrarian economy, which was characterized by the production of products such as cotton, sugar and tobacco, among others.